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ea0070aep1 | Adrenal and Cardiovascular Endocrinology | ECE2020

Residual corticosteroid production in autoimmune addison´s disease

Bjorvatn Saevik Åse , Åkerman Anna-Karin , Methlie Paal , Quinkler Marcus , Palmström Jörgensen Anders , Höybye Charlotte , Debowska Aleksandra J , Gunnar Nedrebø Bjørn , Lise Dahle Anne , Carlsen Siri , Tomkowicz Aneta , Therese Sollid Stina , Nermoen Ingrid , Grønning Kaja , Dahlqvist Per , Grimnes Guri , Skov Jakob , Finnes Trine , Valland Susanna F , Wahlberg Jeanette , Emblem Holte Synnøve , Simunkova Katerina , Kämpe Olle , Sverre Husebye Eystein , Bensing Sophie , Øksnes Marianne

Background: Previous research show that autoimmune adrenal insufficiency develops gradually over time and inexorably results in a total inability to produce adrenal steroids. However, growing evidence suggest that a few patients preserve some steroid producing capacity.Aim: To explore the frequency of residual cortisol production and possible clinical consequences in patients with autoimmune Addison´s disease (AAD).Material an...